Home > Products > Human APIs &Intermediates

  • Product Namecapsaicin
  • CasNo. 2444-46-4
  • MFC17H27NO3
  • MW293.406
  • Purity
  • Appearancesolid
  • Packing
  • Contact usInquiry

Product Details

CasNo： 2444-46-4

MF： C17H27NO3

Appearance： solid

Buy Quality capsaicin 2444-46-4 In Stock with Immediately Delivery

  • Molecular Formula:C17H27NO3
  • Molecular Weight:293.406
  • Appearance/Colour:solid 
  • Vapor Pressure:2.48E-10mmHg at 25°C 
  • Melting Point:54 °C 
  • Refractive Index:1.513 
  • Boiling Point:492.7 °C at 760 mmHg 
  • PKA:9.76±0.20(Predicted) 
  • Flash Point:251.8 °C 
  • PSA：58.56000 
  • Density:1.037 g/cm3 
  • LogP:4.15850 

Nonivamide(Cas 2444-46-4) Usage

Preparation

From nonanyl chloride and vanillylamine.

references

1. m. j. caterina, m. a. schumacher, m. tominaga, t. a. rosen, j. d. levine and d. julius, nature 1997, 389, 816-824. 2. y. g. gil and m. k. kang, life sci 2008, 82, 997-1003. 3. y. s. lee, d. h. nam and j. a. kim, cancer lett 2000, 161, 121-130. 4. h. c. chang, s. t. chen, s. y. chien, s. j. kuo, h. t. tsai and d. r. chen, hum exp toxicol 2011, 30, 1657-1665. 5. k. c. brown, t. r. witte, w. e. hardman, h. luo, y. c. chen, a. b. carpenter, j. k. lau and p. dasgupta, plos one 2010, 5, e10243.>

Definition

ChEBI: A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays.

InChI:InChI=1/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)

2444-46-4 Relevant articles

Preparation method of capsaicin and capsaicin prepared by using method

-

, (2021/06/26)

The invention relates to a capsaicin pre...

Preparation method of capsaicine and capsaicine prepared by method

-

, (2021/04/07)

The invention provides a preparation met...

Novel method for preparing N-(4-hydroxy-3-methoxybenzyl) nonamine without catalyst

-

Paragraph 0018; 0020-0031, (2021/07/14)

The invention belongs to the technical f...

Vanilla amide synthesis method

-

Paragraph 0083-0086; 0099-0101, (2021/06/13)

The invention discloses a vanilla amide ...

2444-46-4 Process route

Nonanoyl chloride
764-85-2

Nonanoyl chloride

Vanillylamin
1196-92-5

Vanillylamin

Nonivamide
2444-46-4,618-92-8

Nonivamide

Conditions
Conditions Yield
Vanillylamin; With sodium hydrogencarbonate; In chloroform; water; at 20 ℃; for 0.75h;
Nonanoyl chloride; In chloroform; water; at 20 - 40 ℃; for 1h;
94%
With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
88.6%
In diethyl ether; N,N-dimethyl-formamide; Ambient temperature;
59%
With diethyl ether;
 
With triethylamine;
 
Nonanoyl chloride
764-85-2

Nonanoyl chloride

vanillylamine hydrochloride
7149-10-2

vanillylamine hydrochloride

Nonivamide
2444-46-4,618-92-8

Nonivamide

Conditions
Conditions Yield
With sodium hydrogencarbonate; In dichloromethane; water; at 20 - 42 ℃; for 2.5h; Temperature;
91.5%
vanillylamine hydrochloride; With sodium hydroxide; In water; N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere; Cooling with ice;
Nonanoyl chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere; Cooling with ice;
60.51%

2444-46-4 Upstream products

  • 764-85-2
    764-85-2

    Nonanoyl chloride

  • 1196-92-5
    1196-92-5

    Vanillylamin

  • 102811-97-2
    102811-97-2

    N-(4-benzyloxy-3-methoxy-benzyl)-nonanamide

  • 90-05-1
    90-05-1

    2-methoxy-phenol

2444-46-4 Downstream products

  • 136449-08-6
    136449-08-6

    N-(4-O-succinic acid-3-methoxybenzyl)-nonamide

  • 146690-24-6
    146690-24-6

    sodium nonivamide acetate

  • 143827-57-0
    143827-57-0

    Glyceryl novinamide

  • 149555-75-9
    149555-75-9

    N-<4-<oxy>-3-methoxybenzyl>nonanamide

Relevant Products

Related products

  • Product NameCasNo.