CasNo： 32981-96-5
0-Deacetylbaccatin III (10-DAB) is a white solid chemical compound that has many uses, including:
Chemical intermediate
10-DAB is used as a raw material in the semi-synthetic production of the anti-cancer drugs paclitaxel (Taxol) and docetaxel (Taxotere). Taxol is used to treat a variety of aggressive carcinomas, while docetaxel is a potent anticancer compound. 10-DAB is also used to study the biosynthetic pathway of taxol.
Antineoplastic agent
10-DAB is an antineoplastic agent and has been reported to be effective against *L. donovani*. It is also nontoxic to human macrophages at concentrations up to 5 μM.
10-Deacetylbaccatin III is a natural product found in Taxus sumatrana, Taxus cuspidata, and other organisms with data available.
