• Product NameCetrorelix Acetate
  • CasNo. 120287-85-6
  • MFC70H92ClN17O14
  • MW1431.06
  • Purity
  • AppearanceWhite powder
  • Packing
  • Contact usInquiry

Product Details

CasNo: 120287-85-6

MF: C70H92ClN17O14

Appearance: White powder

Top Quality Cetrorelix Acetate 120287-85-6 Hot Sell In Stock

  • Molecular Formula:C70H92ClN17O14
  • Molecular Weight:1431.06
  • Appearance/Colour:White powder 
  • Refractive Index:1.667 
  • PKA:9.82±0.15(Predicted) 
  • PSA:495.67000 
  • Density:1.42 g/cm3 
  • LogP:5.93230 

Cetrorelix acetate(Cas 120287-85-6) Usage

Cetrorelix is used to prevent premature ovulation as part of controlled ovarian stimulation treatment. The content of 1 vial (0.25 mg) is administered once a day every 24 hours. In individual cases, it can also be given twice a day at intervals of 12 hours.

InChI:InChI=1/C70H92ClN17O14/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102)/t40-,50-,51+,52+,53-,54-,55+,56-,57-,58?/m1/s1

 

WLP Ingredient Inc was formerly known as Green Valley Biochemical, which was founded in Hong Kong  In 2023, it reached a long-term strategic cooperation agreement with a local factory of plant extrac ,which already got HAHAL,KOSHER,ISO9001,ISO2200,HACCP,cGMP. Now it has developed into a comprehensive enterprise integrating R&D, production and sales. And after years of market accumulation and in response to customer needs, we have close cooperation in various fields and production such as human APIs, veterinary APIs, food additives, feed additives, vitamins, amino acids, etc In the course of business, our company has always adhered to the principle of integrity first and won the praise of our customers. we hope that in the days to come,we can become your important partner and create a better future together.

120287-85-6 Relevant articles

The effect of NMeTyr5 substitution in luteinizing hormone-releasing hormone antagonists.

Haviv,Fitzpatrick,Nichols,Swenson,Mort,Bush,Diaz,Nguyen,Holst,Cybulski,et al.

, p. 928 - 933 (1993)

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Is a lower dose of cetrorelix acetate effective for prevention of LH surge during controlled ovarian hyperstimulation?

Heng-Ju Chen,1,2 Yu-Hung Lin,1,2 Bih-Chwen Hsieh,1,2 Kok-Min Seow,1 Jiann-Loung Hwang,corresponding author1,2,3 and Chii-Ruey Tzeng3

J Assist Reprod Genet. 2006 Jun; 23(6): 289–292.

The use of cetrorelix acetate, a type of GnRH antagonists, in multiple daily injection to prevent LH surge during controlled ovarian hyperstimulation, was proposed by Diedrich et al. [1]. In order to determine the minimal effective dose, Albano et al. have compared daily doses of 0.5, 0.25 and 0.1 mg of cetrorelix in women undergoing IVF.

120287-85-6 Process route

Ac-D-Nal-D-Cpa-D-Pal-Ser(tBu)-Tyr(tBu)-D-Cit-Leu-Arg(Pbf)-Pro-D-Ala-NH<sub>2</sub>

Ac-D-Nal-D-Cpa-D-Pal-Ser(tBu)-Tyr(tBu)-D-Cit-Leu-Arg(Pbf)-Pro-D-Ala-NH2

cetrorelix
120287-85-6

cetrorelix

Conditions
Conditions Yield
With chlorotriisopropylsilane; ethane-1,2-dithiol; trifluoroacetic acid; at 20 ℃; for 2h;
 
1-(tert-butoxycarbonyl)-L-proline
15761-39-4,59433-50-0

1-(tert-butoxycarbonyl)-L-proline

<i>N</i>-<i>tert</i>-butoxycarbonyl-<i>L</i>-leucine
13139-15-6,53296-34-7

N-tert-butoxycarbonyl-L-leucine

Boc-(R)-Ala
3744-87-4,7764-95-6,15761-38-3

Boc-(R)-Ala

Boc-Arg(Tos)-OH
13836-37-8

Boc-Arg(Tos)-OH

cetrorelix
120287-85-6

cetrorelix

Conditions
Conditions Yield
Multistep reaction;
 

120287-85-6 Upstream products

  • 15761-39-4
    15761-39-4

    1-(tert-butoxycarbonyl)-L-proline

  • 13139-15-6
    13139-15-6

    N-tert-butoxycarbonyl-L-leucine

  • 3744-87-4
    3744-87-4

    Boc-(R)-Ala

  • 13836-37-8
    13836-37-8

    Boc-Arg(Tos)-OH

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