CasNo： 50-78-2
MF： C9H8O4
Appearance： white solid
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Acetylsalicylic acid is available as capsules, tablets, enteric-coated tablets (Ecotrin), timed-release tablets (ZORprin), buffered tablets (Ascriptin, Bufferin), and as rectal suppositories. Sodium salicylate is available generically. Other salicylates include choline salicylate (Arthropan), choline magnesium trisalicylate (Trilisate), and magnesium salicylate (Momentum).
Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. Acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Acetylsalicylic acid also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.
acetic anhydride
4'-Methoxy-flavyliumchlorid
4-methoxybenzoic acid
aspirin
| Conditions | Yield |
|---|---|
|
With ruthenium(IV) oxide; sodium periodate; 1) 5 h, room temp., pyridine; 2) acetic ester, water, 20 min : decomposition reaction;
|
52% 79% |
|
With ruthenium(IV) oxide; sodium periodate; Yield given. Multistep reaction. Yields of byproduct given; 1) 5 h, room temp., pyridine; 2) water, acetic ester, 20 min;
|
2-Acetoxy-benzoic acid 2-formyl-4-methyl-phenyl ester
2-hydroxy-5-methylbenzaldehyde
aspirin
| Conditions | Yield |
|---|---|
|
With hydroxide; In 1,4-dioxane; water; at 37 ℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.);
|
The CAS number of Acetylsalicylic acid is 50-78-2.
More information of Acetylsalicylic acid 50-78-2 are:
|
CAS Number |
50-78-2 |
|
Density |
1.35 |
|
Melting Point |
134-136 °C(lit.) |
|
Boiling Point |
321.4 °C at 760 mmHg |
|
Flash Point |
131.1 °C |
|
Vapor Pressure |
0.000124mmHg at 25°C |
|
Refractive Index |
1.4500 (estimate) |
|
HS CODE |
3004.90 |
|
PSA |
63.60000 |
|
LogP |
1.31010 |
|
Pka |
3.5(at 25℃) |
Synonyms for Acetylsalicylic acid 50-78-2:Rhodine(7CI);Salicylic acid acetate (8CI);2-(Acetyloxy)benzoic acid;AC 5230;Acetophen;Acetysal;Acimetten;Acisal;Saletin;Solpyron;Supac;Temperal;Toldex;Trombyl;Yasta;o-(Acetyloxy)benzoic acid;Acetyl Salicylic Acid;Adiro;Asaflow;Asagran;Asatard;Ascoden 30;Ascriptin;Aspalon;Aspirdrops;Aspirin;Aspirin Protect 300;Aspirin-Direkt;Aspro;Aspropharm;Astrix;Benaspir;Bialpirinia;Caprin;Coricidin D;Dolean pH 8;Easprin;Ecotrin;Endosprin;Entericin;Ewin;Extren;Gelprin;
The chemical formula of Acetylsalicylic acid is C9H8O4 which containing 9 Carbon atoms,8 Hydrogen atoms and 4 Oxygen atoms,and the molecular weight of Acetylsalicylic acid is 180.16.
Acetylsalicylic acid is a white crystalline powder commonly known by its common name as aspirin or ASA. Aspirin is the most widely used medication in the world.
InChI:InChI=1/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)/p-1
Relevant articles related to Acetylsalicylic acid:
|
Article |
Source |
|
Bioreductively-activated prodrugs for targeting hypoxic tissue: Elimination of aspirin from 2-nitroimidazole derivatives |
Everett,Naylor,Patel,Stratford,Wardman , p. 1267 - 1272 (1999) |
|
Catalytic method for synthesis of aspirin by a green, efficient and recyclable solid acid catalyst (Preyssler's anion) at room temperature |
Bamoharram, Fatemeh F.,Heravi, Majid M.,Roshani, Mina,Gharib, Ali,Jahangir, Manouchehr , p. 1017 - 1020 (2007) |
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