What is the 4-Acetamidophenol?

4-Acetamidophenol is White crystalline powder, while it's Molecular Formula is C8H9NO2. White crystalline powder Acetaminophen is widely used as an analgesic and fever-reducing agent. Acetaminophen isdesigned for moderate analgesia. It is also effective like aspirin and is used in analgesia forheadaches (from weak to moderate pain), myalgia, arthralgia, chronic pain, for oncological andpost-operational pain, etc.

What is 4-Acetamidophenol (103-90-2) used for?

Acetaminophen is an analgesic and antipyretic compound. Unlike many NSAIDs, which inhibit both COX-1 and COX-2, early studies suggested that acetaminophen is a poor inhibitor of both isoforms. However, it does inhibit COX-2 by 83% and COX-1 by 56% in human blood ex vivo, albeit at a high 1,000 mg dose, with IC50 values of 25.8 and 113.7 μM, respectively. Acetaminophen is enzymatically and non-enzymatically converted to several reactive metabolites that contribute to adverse or indirect effects, including liver injury. At toxic doses, the acetaminophen metabolite N-acetyl-4-benzoquinone imine (NAPQI; ) depletes glutathione reserves in the liver, leading to an accumulation of NAPQI and subsequent hepatocyte necrosis. Acetaminophen decreases glutathione levels and reduces glutathione peroxidase activity in mice when administered at a dose of 250 mg/kg and induces ferroptotic cell death in primary mouse hepatocytes, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . Acetaminophen has analgesic and antipyretic properties in animal models.InChI:InChI=1/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/i2D,3D,4D,5D

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Product NameParacetamol
CasNo. 103-90-2
MFC₈H₉NO₂
MW151.165
Purity
AppearanceWhite crystalline powder
Packing
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Product Details

CasNo： 103-90-2

MF： C₈H₉NO₂

Appearance： White crystalline powder